
Targeted drug delivery
Chronic pain
Patient selection and clinical evidence
Contraindications include infection; implant depth greater than 2.5 cm below skin; insufficient body size; spinal anomalies; drugs with preservatives, drug contraindications, drug formulations with pH ≤3, use of catheter access port (CAP) kit for refills or of refill kit for catheter access, blood sampling through CAP in vascular applications, use of the personal therapy manager (PTM) to administer opioid to opioid-naïve patients. See SynchroMed™ product labeling for more information.