Targeted drug delivery
Conditions
Alleviate chronic pain, cancer pain, and severe spasticity
Less pain and severe spasticity. Fewer side effects.
Millions of Americans are affected by pain and have been prescribed systemic opioids, typically oral, as part of their treatment plan by healthcare providers.1 A common medication for spasticity is a muscle relaxer called baclofen. The implanted pump stores and dispenses medication inside the body, reducing the opportunity for diversion of the drug, for misuse by individuals who are not prescribed the opiods or baclofen. Additionally, the physician programs the pump to deliver a certain amount of medication, allowing more physician control compared to systemic opioid therapy, reducing the opportunity for misuse of prescribed opioids.
Improved quality of life
87%
of pain patients who rated their quality of life as fair to excellent2
Benefits of targeted drug delivery
Benefits of treating chronic intractable pain with targeted drug delivery include:
- Effective pain relief3,4
- Reduced or eliminated use of oral pain medicines4,13
- Improved ability to function and participate in day-to-day activities5
- Fewer side effects compared to oral medication6
- Patient satisfaction4,7
- Cost benefits8,9
In clinical studies, the test dose was effective for:
94%
of patients with spasticity related to the brain2
97%
of patients with spasticity related to the spine10
Alleviating intractable cancer pain
Cancer patients may benefit from targeted drug delivery, an alternate route of delivering pain medication.
Targeted drug delivery is effective in reducing or eliminating the need for systemic opioids when used to treat malignant pain.11
A different option for severe spasticity
The SynchroMed™ III implantable infusion system delivers baclofen directly into the intrathecal space, thereby bypassing the blood-brain barrier. As a result, only a fraction of the oral dose is needed to produce efficacy while minimizing systemic side effects.12