Cardiac ablation and mapping
Clinical evidence
Explore clinical studies and evidence that evaluate our novel cardiac ablation technologies.
SPHERE Per-AF IDE trial
SPHERE Per-AF was the first pulsed field ablation (PFA) randomized, single-blind, non-inferiority trial of persistent AF patients comparing the Sphere-9™ catheter with the Affera™ mapping and ablation system (investigational arm) to the Thermocool STSF™* SMARTTOUCH®* SF radiofrequency ablation catheter with the CARTO®* 3 system (control arm).
PULSED AF trial
PULSED AF evaluated the safety and effectiveness of the PulseSelect™ pulsed field ablation (PFA) system for the treatment of patients with paroxysmal (PAF) or persistent (PsAF) atrial fibrillation.
STOP AF First trial
View data from the clinical trial assessing initial rhythm control of paroxysmal AF with cryoballoon ablation versus antiarrhythmic drugs.
STOP Persistent AF trial
View information on this clinical trial assessing the safety and efficacy of the Medtronic cryoballoon in treating persistent AF patients.
DIAMOND-AF trial
In this trial, the DiamondTemp™ ablation system was compared to a contact force-sensing ablation system (CF-RF).
ICY-AVNRT trial
This trial assessed the use of the Freezor™ Xtra cardiac cryoablation catheter in treating AVNRT.
STOP AF trial
Learn more about this randomized study on the effectiveness of the Arctic Front™ and Arctic Front Advance™ cardiac cryoablation catheters.
Fire and Ice trial
Discover information on this 1:1 randomized, noninferiority study comparing cryoballoon and radiofrequency ablation.