Liquid embolics

Onyx™ liquid embolic system

Liquid embolics

Onyx™ liquid embolic system

The Onyx™ liquid embolic system (LES) is an injectable, non-adhesive agent used for presurgical embolization of brain arteriovenous malformations (bAVMs).

Description

The Onyx™ Confidence: Performance you can trust.

Designed to provide complete filling and distal penetration, the Onyx™ LES is a pre-mixed, radiopaque, injectable liquid embolic made of ethylene vinyl-alcohol copolymer (EVOH), dimethyl sulfoxide (DMSO), and micronized tantalum powder (Ta).1

Features


Control2

Cohesive deposition

Provides a responsive, controlled injection of Onyx™ LES to achieve nidal penetration

Visibility2

Know where it flows

Provides live feedback of the embolic fill & trajectory, enabling visibility of Onyx™ injection under fluoroscopy

Evidence3,4

Market Leader

330+ publications on Onyx™ LES and on market for 19 years

Please note that some of these studies were conducted OUS and may not comply with the U.S. indications for use. See IFU for U.S. indication.

Onyx™ LES is available in different formulations and viscosities1

The numerical term of Onyx™ LES describes its relative viscosity. Onyx™ LES is offered in 18 and 34 to provide options for controllable injections.

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Onyx™ LES compatible flow-directed micro catheters

The Apollo™ Onyx™ and Marathon™,‡ delivery micro catheters have been expressly designed to complement and enhance embolization with Onyx™ LES. These synergistic tools help you journey to more tortuous locations, embolize more challenging lesions, and return with confidence.5-7

 Based on bench testing. May not be representative of clinical performance.

Marathon™ and Apollo™ flow-directed catheters have been expressly designed to complement and enhance embolization with Onyx™ LES.

Ordering information

Onyx™ liquid embolic system

Item number Description
105-7100-060 Onyx™ 18 formulation kit contains: 1.5 mL vial of Onyx™ LES, 1.5 mL vial of DMSO, 1 mL DMSO syringe, 2X
105-7100-080 Onyx™ 34 formulation kit contains: 1.5 mL vial of Onyx™ LES, 1.5 mL vial of DMSO, 1 mL DMSO syringe, 2X

Onyx™ liquid embolic system accessories

Item number Description Units per box
103-1205-001 Vial mixer, 15–17 mm, 110 V 1
103-1205-002 Vial mixer, 15–17 mm, 240 V 1

  1. Onyx™ Liquid Embolic System IFU, 70862-001 Rev 10/13.
  2. Based on internal design verification test report #TR02-092 Rev A, Low Density Onyx™ (18, 20, and 34) with Increased Tantalum Concentrations. 
  3. Onyx™ LES PMA #P030004.
  4. Based on internal clinical evaluation (literature review) report #TR-NV12982 Rev L, Onyx™ LES, 1 mL Onyx™ LES Delivery Syringe, and Onyx Syringe Catheter Interface Adaptor.
  5. Apollo™ Onyx™ Delivery Micro Catheter IFU, 70556-001 Rev. 05/13.
  6. Based on internal design verification test report #TR03-106 Rev A, Marathon™ AVM Catheter Model #: 105-5055.
  7. Meyers PM et al., Safety of the Apollo™ Onyx™ delivery microcatheter for embolization of brain arteriovenous malformations: results from a prospective post-market study. J Neurointerv Surg. 2021 Oct;13(10):935-941. doi: 10.1136/neurintsurg-2020-016830. Epub 2021 Feb 1. PMID: 33526480.