SYMPLICITY™ BLOOD PRESSURE PROCEDURE
Benefits and risks
The Symplicity™ blood pressure procedure complements typical treatments to help reduce high blood pressure,1,2 which is shown to lower your risk of serious health problems.3

Reducing blood pressure by 10 mmHg can lower your risk of 3:
heart failure
↓28%
cardiovascular events
↓20%
stroke
↓27%
Benefits

Beyond another daily blood pressure pill
The Symplicity™ procedure complements typical blood pressure treatments like lifestyle changes and medications. While it may not affect how many medications you take, it may help you avoid adding another pill to your daily regimen.1,2
Proven to help beyond medications
The Symplicity™ procedure is proven to safely help lower blood pressure in people who are taking blood pressure medication and those who are not.1,2
Risks
What are the risks of the Symplicity™ blood pressure procedure?4
As with any minimally invasive procedure, the Symplicity™ blood pressure procedure does have known risks. These risks should be considered in relation to the potential benefits of the procedure. Adverse events include, but are not limited to, bruising and pain.
Not every person will experience the same results. Talk to your doctor to see if the Symplicity™ procedure is right for you. Your doctor should discuss all potential benefits and risks with you.
Is the Symplicity™ blood pressure procedure right for you?
Answer a few simple questions, and then talk to your doctor to see if the procedure may be right for you.

Find a Symplicity™ specialist.
Here’s how you can find a doctor near you who is experienced in the Symplicity™ blood pressure procedure.
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1. Kandzari DE, Townsend RR, Kario K, et al. Safety and efficacy of renal denervation in patients taking antihypertensive medications. J Am Coll Cardiol. 2023;82(19):1809–1823. doi: 10.1016/j.jacc.2023.08.045.
2. Böhm M, Kario K, Kandzari DE, et al. Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomised, sham-controlled trial. Lancet. 2020;395(10234):1444–1451. doi: 10.1016/S0140-6736(20)30554-7.
3. Ettehad D, Emdin CA, Kiran A, et al. Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis. Lancet. 2016;387(10022):957–967. doi: 10.1016/S0140-6736(15)01225-8.
4. Medtronic Symplicity Spyral™ multi-electrode renal denervation catheter instructions for use. Medtronic; 2023.