Brain channel monitoring

BIS™ monitoring system

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Brain channel monitoring

BIS™ monitoring system

The Bispectral Index™ (BIS™) monitoring system processes raw EEG information to provide a direct measurement of the patient’s level of consciousness.

Description

Proven algorithm. Trusted insight.

Too much or too little anesthesia can be associated with challenges such as longer recovery times and postoperative neurocognitive disorders. The BIS™ technology is intended to reflect the anesthetic effect on each patient’s brain which helps you to personalize dosing to improve emergence and recovery times.1–4

  • Use up to 38% less anesthetic agent.1,5–8
  • Patients monitored with BIS™ technology have been shown to wake up 27–53% faster in the OR.1,7–9
  • Postoperative delirium is reduced up to 29%.10

Features

BIS™ complete 4-channel and 2-channel monitors

The BIS™ monitor translates the raw EEG data into the easy-to-read BIS™ index.

Both 2-channel and 4-channel monitors provide:

  • User-configurable display
  • Versatile platform for future expandability

The 4-channel monitor provides:

  • EEG monitoring
  • Asymmetry indicator (ASYM)
  • Ability to trend BIS™-left and BIS™-right values

See the evidence for the BIS™ proven algorithm.

A circular illustration representing 38%

Use up to 38% less anesthetic agents.1,5-8

A circular illustration representing a 27 to 53 percent range

Patients monitored with BIS™ technology have been shown to wake up 27–53% faster in the OR.1,7-9

A circular illustration representing 87 percent

87% increase in “excellent/fully oriented” status on PACU admission.8

Clinical evidence

Improved post anesthesia recovery

“The pooled data showed that the use of BIS™ was significantly associated with a lower incidence of POCD and improved recovery parameters (extubation time, time to eye opening, and time to discharge from the PACU).”11

 

Wei Zhuen Chew

Improved post anesthesia neurocognitive outcomes

“We found that BIS™ monitoring of the depth of anesthesia prevented POD, whereas EEG monitoring was not effective. BIS™ quantifies the depth of anesthesia based on EEGs, which enables a more accurate control of anesthetic concentration and increases patient safely.”12

 

Xia Li, et al.

Decrease intraoperative awareness

“… in intravenous anesthesia, BIS™ monitoring could reduce the incidence of intraoperative awareness by approximately 80%.”13

 

Wen-Wei Gao

Frequently asked questions

Ordering information

Item number Description Units per box
186-0210 BIS™ complete 2-channel monitoring system 1
186-0195-AM BIS™ LoC 2-channel monitor with patient interface cable 1
186-0224-AMS BIS™ LoC 4-channel monitoring system with patient interface cable 1
186-1046 BIS™ Vista monitor 1
536-0047 Power cord 6′ (North America) 1

The BIS™ monitoring system should not be used as the sole basis for diagnosis or therapy and is intended only as an adjunct in patient assessment. Reliance on the BIS™ monitoring system alone for intraoperative anesthetic management is not recommended.

  1. Lewis SR, Pritchard MW, Fawcett LJ, Punjasawadwong Y. Bispectral index™ for improving intraoperative awareness and early postoperative recovery in adults. Cochrane Database Syst Rev. 2019;9:CD003843. doi:10.1002/14651858.CD003843.pub4.
  2. Zhang C, Xu L, Ma Y-Q, et al. Bispectral index™ monitoring prevent awareness during total intravenous anesthesia: a prospective, randomized, double-blinded, multi-center controlled trial. Chin Med J (Engl). 2011;124(22):3664–3669.
  3. Myles PS, Leslie K, McNeil J, Forbes A, Chan MT. Bispectral index™ monitoring to prevent awareness during anaesthesia: The B-Aware randomised controlled trial. Lancet. 2004;363(9423):1757-1763. doi:10.1016/S0140-6736(04)16300–9.
  4. Ekman A, Lindholm ML, Lennmarken C, Sandin R. Reduction in the incidence of awareness using BIS™ monitoring. Acta Anaesthesiol Scand. 2004;48(1):20-26. doi:10.1111/j.1399–6576.2004.00260.x.
  5. Punjasawadwong Y, Phongchiewboon A, Bunchungmongkol N. Bispectral index™ for improving anaesthetic delivery and postoperative recovery. Cochrane Database Syst Rev. 2014;(6):CD003843. doi:10.1002/14651858.CD003843.pub3.
  6. Luginbuhl M, Wuthrich S, Petersen-Felix S, Zbinden AM, Schnider TW. Different benefit of bispectal index™ (BIS™) in desflurane and propofol anesthesia. Acta Anaesthesiol Scand. 2003;47(2):165–73.
  7. Song D, Joshi GP, White PF. Titration of volatile anesthetics using bispectral index™ facilitates recovery after ambulatory anesthesia. Anesthesiology. 1997;87(4):842–848.
  8. Gan TJ, Glass PS, Windsor A, et al. Bispectral index™ monitoring allows faster emergence and improved recovery … . Anesthesiology. 1997;87(4):808–815. doi:10.1097/00000542-199710000-00014.
  9. Wong J, Song D, Blanshard H, Grady D, Chung F. Titration of isoflurane using BIS™ index improves early recovery of elderly patients undergoing orthopedic surgeries. Can J Anaesth. 2002;49(1):13–18. doi:10.1007/BF03020413.
  10. Punjasawadwong Y, Chau-In W, Laopaiboon M, Punjasawadwong S, Pin-On P. Processed electroencephalogram and evoked potential techniques for amelioration of postoperative delirium and cognitive dysfunction following non-cardiac and non-neurosurgical procedures in adults. Cochrane Database Syst Rev. 2018;5:CD01128.

  1. Chew WZ, Teoh WY, Sivanesan N, San Loh P, Shariffuddin II, Ti LK, Ng KT. Bispectral index™ (BIS™) monitoring and postoperative delirium in elderly patients undergoing surgery: A systematic review and meta-analysis with trial sequential analysis. J. Cardiothorac. Vasc. Anesth. 2022 1;36(12):4449–4459.
  2. Li X, Wang Y, Liu J, Xiong Y, Chen S, Han J, Xie W, Wu Q. Effects of perioperative interventions for preventing postoperative delirium: A protocol for systematic review and meta-analysis of randomized controlled trials. Medicine. 2021 7;100(29).
  3. Gao WW, He YH, Liu L, Yuan Q, Wang YF, Zhao B. BIS™ monitoring on intraoperative awareness: a meta-analysis. Current Medical Science. 2018;38(2):349–353.