Exhibiting a significant proportion of asynchronous breaths is associated with an almost five-fold increase in ICU mortality,1 a three-fold increase in median duration of mechanical ventilation and a greater than two-fold increase in median hospital length of stay.2
1. Blanch L, Villagra A, Sales B, et al. Asynchronies during mechanical ventilation are associated with mortality. Intensive care medicine. 2015;41(4):633-641.
View Abstract2. de Wit M, Miller KB, Green DA, Ostman HE, Gennings C, Epstein SK. Ineffective triggering predicts increased duration of mechanical ventilation. Critical care medicine. 2009;37(10):2740-2745.
View Abstract3. Vignaux L, Grazioli S, Piquilloud L, et al. Patient-ventilator asynchrony during noninvasive pressure support ventilation and neurally adjusted ventilatory assist in infants and children. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 2013;14(8):e357-364.
View Abstract4. Gentile MA. Cycling of the mechanical ventilator breath. Respiratory care. 2011;56(1):52-60.
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