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Exhibiting a significant proportion of asynchronous breaths is associated with an almost five-fold increase in ICU mortality,1 a three-fold increase in median duration of mechanical ventilation and a greater than two-fold increase in median hospital length of stay.2
Approximately 36% of patients admitted to the ICU require mechanical ventilation.3 Those patients who endure a prolonged time on mechanical ventilation are at-risk for greater resource utilization and length of stay. 4Therefore a great deal of clinical focus has developed around optimizing the delivery of mechanical ventilation and subsequent weaning. An increasing amount of evidence is revealing the relationship between patient-ventilator asynchrony (PAV) and adverse outcome in mechanically ventilated patients including increased time on mechanical ventilation and mortality.1,2 Therefore, the identification, prevention and resolution of patient-ventilator asynchrony is increasingly being recognized as being integral to the optimization of quality of care for mechanically ventilated patients.
Up to 25% of patients with acute respiratory failure exhibit a significant proportion of asynchronous breaths (>10 %)5
Exhibiting a significant proportion of asynchronous breaths is associated with an almost five-fold increase in ICU mortality,1 a three-fold increase in median duration of mechanical ventilation and a greater than two-fold increase in median hospital length of stay.2
Patient-ventilator asynchrony consists of multiple types of asynchrony. The identification and treatment of each type is multifactorial, influenced by a myriad of ventilator-related and patient-specific factors.6