TREATMENT OPTIONS

Cyanoacrylate Ablation

A minimally invasive procedure delivers a small amount of a specially formulated medical adhesive to seal — or close — the diseased vein, rerouting blood to nearby healthy veins.

Cyanoacrylate ablation

Cyanoacrylate ablation is a procedure performed by your doctor that is designed to close diseased veins with a medical adhesive delivered through a small catheter.

This is a 30- to 60-minute outpatient (same-day) procedure that can be performed on both legs with minimal pain and requires no tumescent anaesthesia.

Step-by-step Cyanoacrylate ablation procedure

STEP 01

Before therapy

You will have an ultrasound imaging exam of the leg being treated. This exam is important for assessing the diseased superficial vein and planning the procedure.

Step-by-step procedure

STEP 02

During therapy

The site where the doctor will access your vein will be numbed by a needle stick.
Once numb your doctor will insert the catheter (i.e., a small hollow tube) into your leg. You may feel some pressure from the placement of the catheter.
The catheter will be placed in specific areas along the diseased vein to deliver small amounts of the medical adhesive. You may feel a mild sensation of pulling. An ultrasound will be used during the procedure to guide and position the catheter.

This is an image of a male healthcare professional consulting with female patient.

Step-by-step procedure

STEP 03

After therapy

Following the procedure, your doctor will apply a simple bandage over the insertion site and will give you compression stockings to aid in the healing process. Your doctor may encourage you to walk and to refrain from extended standing and strenuous activities for a period of time. The average patient typically resumes normal activities within a few days.^1,2
Your doctor will recommend follow-up care as needed¹

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The procedure

– Catheter is placed in the vein

– Specialised adhesive is placed

– Light external pressure is applied

– Catheter is removed

More information

Benefits of the procedure

Same day outpatient procedure
In a sample of 108 patients, 67.6% of patients experienced no bruising, with 26.9% experiencing <25% area of bruising at day 3 post-procedure¹
94.6% closure rate at five years¹
Compression stockings may not be needed after the procedure^2,3

Risks

The Cyanoacrylate Ablation procedure is minimally invasive and catheter-based. As such, it may involve the following risks.

Allergic reaction to the adhesive
Arteriovenous fistula (i.e., an abnormal connection between an artery and a vein)
Bleeding from the access site
Deep vein thrombosis (i.e., blood clot in the deep vein system)
Oedema (i.e., swelling) in the treated leg
Haemotoma (i.e., the collection of blood outside of a vessel)
Hyperpigmentation (i.e., darkening of the skin)
Infection at the access site
Neurological deficits including stroke and death
Non-specific mild inflammation of the cutaneous and subcutaneous tissue
Pain
Paresthesia (i.e., a feeling of tingling, pricking, numbness or burning)
Phlebitis (i.e., inflammation of a vein)
Pulmonary embolism (i.e., blockage of an artery in the lungs)
Urticaria (i.e., hives) or ulceration may occur at the site of injection
Vascular rupture and perforation
Visible scarring

Medtronic provides this listing as a service. We have no vested interest in any specific physicians, nor do we provide any recommendation, assurance, or guarantee with respect to their service. This listing may not be a complete list of all physicians who provide this service. Information on this site should not be used as a substitute for talking with your doctor. Always talk with your doctor about diagnosis and treatment information.

References

1.Morrison N, Gibson K, McEnroe S, et al. Randomized trial comparing cyanoacrylate embolization and radiofrequency ablation for incompetent great saphenous veins (VeClose). J Vasc Surg. April 2015;61(4):985-994.

2.Proebstle T, Alm J, Dimitri S, et al. Three-year follow-up results of the prospective European Multicenter Cohort Study on Cyanoacrylate Embolization for treatment of refluxing great saphenous veins. J Vasc Surg Venous Lymphat Disord. March 2021;9(2):329-334.

3.Almeida JI, Javier JJ, Mackay EG, Bautista C, Cher DJ, Proebstle TM. Thirty-sixth-month follow-up of first-in-human use of cyanoacrylate adhesive for treatment of saphenous vein incompetence. J Vasc Surg Venous Lymphat Disord. September 2017;5(5):658-666.

4.Morrison N, Gibson, Vasquez M, et al. VeClose trial 12-month outcomes of cyanoacrylate closure versus radiofrequency ablation for incompetent great saphenous veins. J Vasc Surg Venous Lymphat Disord. May 2017;5(3):321-330.

Information on this site should not be used as a substitute for talking with your doctor. Always talk with your doctor about diagnosis and treatment information

Cyanoacrylate Ablation

A minimally invasive procedure delivers a small amount of a specially formulated medical adhesive to seal — or close — the diseased vein, rerouting blood to nearby healthy veins.