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Clinical Evidence Cardiac Ablation for Atrial Fibrillation

Alert Indications, Safety, and Warnings

Stop AF First Clinical Trial

This prospective, multicenter randomized study was designed to evaluate the safety and effectiveness of the Medtronic cryoablation system as an initial first-line rhythm control treatment in patients with symptomatic paroxysmal atrial fibrillation (PAF).

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Arctic Front Advance Pro cryoballoon shown in a mirror image of itself lying flat on a blue gradient background

Stop Persistent AF Clinical Trial

This prospective, multicenter, single-arm clinical trial assessed the safety and efficacy of PVI with the Medtronic cryoballoon for treating drug refractory, symptomatic, persistent AF.

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Stop AF Trial And Stop AF Post-approval Study

These two pivotal trials assessed the safety and effectiveness of the Arctic Front and Arctic Front Advance™ cardiac cryoablation catheters.

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Outcomes

Clinical Trials

View the results of multiple clinical trials highlighting the unique benefits of cryo energy.

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Fire and Ice AF Ablation Clinical Trial

This multicenter, randomized trial compared the efficacy and safety of PVI using cryoablation versus radiofrequency (RFC) ablation.

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