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EVIDENCE ON CLINICAL VALUE

IONM DURING THYROID/PARATHYROID/EAR SURGERIES OR PAROTIDECTOMIES - SUMMARY

clincal value

EVIDENCE FROM SINGLE-BLINDED RCTs: INTERMITTENT IONM REDUCED THE INCIDENCE OF NERVE PALSY/PARESIS DURING TOTAL THYROIDECTOMIES AND BILATERAL THYROID SURGERIES

evidence

REAL-WORLD EVIDENCE FROM 8,900 PATIENTS IN GERMANY: INTERMITTENT IONM REDUCED THE RATE OF EARLY & PERMANENT PALSIES

Intermittent IONM significantly reduced the rate of overall postoperative early & permanent RLN palsies among thyroid surgery patients and patients undergoing high-risk procedures (recurrent goiter, thyroid carcinoma) compared to visualization alone20

evidence from 8,900 pateints

EVIDENCE FROM A NON-RCT: INTERMITTENT IONM REDUCED THE RATE OF TRANSIENT & PERMANENT PALSIES

Compared to visualization, intermittent IONM significantly reduced the rate of transient and permanent palsies of the RLN (nerves at risk)21

evidence from non-rtc

EVIDENCE FROM A RCT: INTERMITTENT IONM ENHANCED THE RECOVERY OF RLN FUNCTION

The severity of voice disorders was significantly reduced by intermittent IONM compared to visualization alone following thyroid surgery22

evidence from a rtc

EVIDENCE FROM A RCT: INTERMITTENT IONM ENHANCED THE RECOVERY OF FACIAL NERVE FUNCTION26

evidence from a rtc
evidence from a rtc

EVIDENCE FROM A RCT: INTERMITTENT IONM
RESULTED IN EARLIER RECOVERY OF FACIAL FUNCTION

Compared to visualization, a significantly higher percentage of patients had earlier recovery of facial function after surgery for recurrent pleomorphic adenoma when facilitated by intermittent IONM26

evidence from a rtc

EVIDENCE BASED ON POOLED ANALYSIS: INTERMITTENT IONM RESULTED IN A HIGHER RATE OF FACIAL NERVE PRESERVATION

Intermittent IONM resulted in a significantly higher percentage of patients with FN preservation compared to visualization after surgery for acoustic neuroma25

pooled analysis

INTERMITTENT IONM REDUCED THE RATE
OF FACIAL NERVE PARESIS

IONM significantly reduced the rate of postoperative FN paresis following parotidectomies compared to visualization in all patients, and in patients without comorbidities and no prior surgeries27

facial nerve analysis

CONTINUOUS IONM REDUCED THE RATE
OF PERMANENT PALSIES

permanent palsies

See the device manual for detailed information regarding the instructions for use, indications, contraindications, warnings, precautions, and potential adverse events. For further information, contact your local Medtronic representative and/or consult the Medtronic website at www.medtronic.com.