Professionisti del settore sanitario

Mosaic™ and Mosaic Ultra™

Bioprostheses

Overview

The Mosaic™ bioprosthesis – based on more than 30 years of Medtronic tissue valve design expertise – is an excellent choice for surgeons looking for long-lasting durability, exceptional performance and implantability for aortic, mitral and MICS procedures.

INDICATIONS

The Mosaic bioprosthesis is for the replacement of malfunctioning native or prosthetic aortic and/or mitral heart valves.

PRODUCT DETAILS

UNDENIABLY DURABLE.

Published clinical experience demonstrates impressive long-term performance in all age groups.

Additional factors that may contribute to durability are:

Proprietary AOA™ anti-calcification tissue treatment that mitigates calcification and protects the tissue^*
Next generation flexible polymer stent allows for absorption of stress produced during the cardiac cycle
The Medtronic Physiologic Fixation^* process minimizes the stress applied to the leaflets during tissue fixation

EXCELLENT CLINICAL OUTCOMES

Excellent Outcomes

EASE OF IMPLANT

Our innovative Cinch™ implant system further capitalizes on the valve’s flexible stent to facilitate valve implantation, particularly through a tight sinotubular space.

It also:

Improves overall visualization
Has stent posts that deflect to allow for easier knot tying near the posts in aortic replacements
Helps prevent suture looping
Facilitates minimally invasive procedures
Protects tissue from inadvertent damage

ADVANCED TISSUE FIXATION

Our exclusive Physiologic Fixation^* process mitigates biomechanical failures and promotes long-term valve durability by:

Improved preservation of valve structure and leaflet function, allowing it to function similar to a native valve
Allowing leaflets to remain soft and flexible which protects the tissue from cyclic fatigue

SUITABILITY FOR FUTURE INTERVENTIONS

Valve dimensions and geometry facilitate future TAV-in-SAV replacements. This includes:

Radiopaque stent post eyelets, which provide visible coaxial markers during TAV-in-SAV procedures
MR conditional, non-metallic frame mitigates risk of corrosion between SAV and TAV stent materials
Interior-mounted leaflets mitigate potential risk of coronary obstruction

Product Specifications

Mosaic™ Aortic Valve, Model 305

Mosaic Aortic Valve, Model 305

Order Number	Valve Size (Stent O.D.^† (±0.5 mm)	Orifice Diameter (Stent O.D. (±0.5 mm)	Suture Ring Diameter (±1 mm)	Valve Height (±0.5 mm)	Aortic Protrusion (±0.5 mm)
Order Number	(A)	(B)	(C)	(D)	(E)
305C219	19	17.5	25.0	13.5	11.0
305C221	21	18.5	27.0	15.0	12.0
305C223	23	20.5	30.0	16.0	13.5
305C225	25	22.5	33.0	17.5	15.0
305C227	27	24.0	36.0	18.5	15.5
305C229	29	26.0	39.0	20.0	16.0

Mosaic™ Mitral Valve, Model 310

Mosaic Mitral Valve, Model 310

Order Number	Valve Size (Stent O.D.^† (±0.5 mm)	Orifice Diameter (Stent O.D. (±0.5 mm)	Suture Ring Diameter (±1 mm)	Valve Height (±0.5 mm)	Ventricular Protrusion (±0.5 mm)
Order Number	(A)	(B)	(C)	(D)	(E)
310C25	25	22.5	33.0	18.0	13.5
310C27	27	24.0	35.0	19.0	14.0
310C29	29	26.0	38.0	20.5	15.5
310C31	31	28.0	41.0	22.0	17.0
310C33	33	30.0	43.0	23.0	17.5

Mosaic Ultra™ Aortic Valve, Model 305

Need image - Mosaic Aortic Valve, Model 305

Order Number	Valve Size (Stent O.D.^† (±0.5 mm)	Orifice Diameter (Stent O.D. (±0.5 mm)	Suture Ring Diameter (±1 mm)	Valve Height (±0.5 mm)	Aortic Protrusion (±0.5 mm)
Order Number	(A)	(B)	(C)	(D)	(E)
305U219	19	17.5	24.0	13.5	11.0
305U221	21	18.5	26.0	15.0	12.0
305U223	23	20.5	28.0	16.0	13.5
305U225	25	22.5	30.0	17.5	15.0
305U227	27	24.0	32.0	18.5	15.5
305U229	29	26.0	34.0	20.0	16.0

Order Number	Description
T7308C	Mosaic Aortic Sizers
T7615M5M	Tray, Accessory, Mosaic, Mitral
T7308U	Tray, Accessory, Mosaic Ultra, Aortic
7308U	Mosaic Ultra Aortic Sizers
7639	Handle (234 mm length) pilant, without locknut handle to be used with Mosaic or Mosaic Ultra prostheses
7639XL	Handle (368 mm length) pilant, without locknut handle to be used with Mosaic or Mosaic Ultra prostheses
7308C	Mosaic Aortic Sizer Set (no handles, no tray)
7310	Mosaic Mitral Obturator Set (no handles, no tray)

No clinical data is available which evaluates the long-term impact of the Physiologic Fixation process or the impact of AOA treatment in patients.

^†

Equivalent to annulus diameter

References

Riess FC, Fradet G, Lavoie A, Legget M. Long-term outcomes of the Mosaic bioprosthesis. Ann Thorac Surg 2018;105:763-769.