Symbotex™ Composite Mesh

1. Based on the results of the Covidien-sponsored preclinical study carried out on a porcine model to validate the design of Symbotex™ composite mesh - Covidien design validation report 0901CR249a (June 2013)

2. Documented in the design verification report issued by Covidien in July 2013 - Covidien design verification report 0901CR247b (July 2013)

3. Size & shape comparison chart

4. Except in cases where transfacial sutures are used as well as meshes in open approach

5. Demonstrated in a preclinical study sponsored by Covidien, carried out on pigs in May 2013 with 6 surgeons and aiming at validating the design of Symbotex™ composite mesh - Covidien internal report 0901CR252a (June 2013)

6. Definition of the Symbotex™ clinging effect observed during the design validation conducted by Covidien in a porcine model in May 2013 - Covidien internal memorandum 0901CR261a (July 2013)

7. Four weeks after implantation

8. Evaluated in a preclinical study sponsored by Covidien, conducted in April 2013, and comparing local tissue effects and integration, collagen film degradation and tissue attachment performance of Symbotex™ composite mesh with Ventralight™* ST mesh and Physiomesh™* flexible composite mesh in a porcine model - Namsa report No.163905 (October 2013)

9. Comparison of the physical and mechanical properties of Symbotex™ composite mesh to those of Parietex™ optimized composite mesh through a bench study conducted by Covidien in July 2013 - Covidien internal report TEX043 (July 2013)