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Incidence and Risk Factors of Postoperative Delirium by Procedure

Study Procedure Incidence of Delirium Elderly? N
Benoit 20051 AAA 33%   102
Sugimoto 20152 AAA 11.50%   397
Gottesman 20103 CABG 6%   5034
Loponen 20084 CABG 6.00%   302
Martin 20105 CABG 6.90%   14301
Martin 20126 CABG 5.80%   8474
Miyazaki 20117 CABG 16.40%   685
Tse 20158 CABG 25%   396
Zhang 20159 CABG 30.52%   249
Chang 200810 Cardiac Surgery 41.70%   288
Koster 201211 Cardiac Surgery 17%   300
Kryzch 201412 Cardiac Surgery 4.10%   8792
Mangusan 201513 Cardiac Surgery 25.50%   656
Smulter 201314 Cardiac Surgery 54.90%   142
Tse 201515 Cardiac Surgery 28%   679
Gottschalk 201516 Hip Fracture Repair 32.90% Yes 459
Guo 201617 Hip Fracture Repair 21% Yes 572
Lee 201118 Hip Fracture Repair 30.20% Yes 232
Mosk 201719 Hip Fracture Repair 35% Yes 566
Yang 201720 Hip Fracture Repair 24% Yes 5364
Zywiel 201521 Hip Fracture Repair 48% Yes 242
Gleason 201522 Major Elective Surgery 23.90% Yes 566
Abelha 201323 Major Elective Surgery 16%   562
Inuoye 201624 Major Elective Surgery 24% Yes 560
Raats 201525 Major Elective Surgery 15% Yes 232
Veiga 201226 Major Elective Surgery 18.80%   680
Abawi 201627 TAVR 13.40%   268
Eide 201528 TAVR 44% Yes 65
Huded 201629 TAVR 21%   294
Maniar 201630 TAVR 29%   168
  • 1. Benoit AG, Campbell BI, Tanner JR, et al. Risk factors and prevalence of perioperative cognitive dysfunction in abdominal aneurysm patients. J Vasc Surg. 2005;42(5):884-890.
  • 2. Sugimoto M, Kodama A, Narita H, Banno H, Yamamoto K, Komori K. Pre- and Intraoperative Predictors of Delirium after Open Abdominal Aortic Aneurysm Repair. Ann Vasc Dis. 2015;8(3):215-219.
  • 3. Gottesman RF, Grega MA, Bailey MM, et al. Delirium after coronary artery bypass graft surgery and late mortality. Ann Neurol. 2010;67(3):338-344.
  • 4. Loponen P, Luther M, Wistbacka JO, et al. Postoperative delirium and health related quality of life after coronary artery bypass grafting. Scand Cardiovasc J. 2008;42(5):337-344.
  • 5. Martin BJ, Buth KJ, Arora RC, Baskett RJ. Delirium as a predictor of sepsis in post-coronary artery bypass grafting patients: a retrospective cohort study. Crit Care. 2010;14(5):R171.
  • 6. Martin BJ, Buth KJ, Arora RC, Baskett RJ. Delirium: a cause for concern beyond the immediate postoperative period. Ann Thorac Surg. 2012;93(4):1114-1120.
  • 7. Miyazaki S, Yoshitani K, Miura N, et al. Risk factors of stroke and delirium after off-pump coronary artery bypass surgery. Interact Cardiovasc Thorac Surg. 2011;12(3):379-383.
  • 8. Tse L, Schwarz SK, Bowering JB, Moore RL, Barr AM. Incidence of and Risk Factors for Delirium After Cardiac Surgery at a Quaternary Care Center: A Retrospective Cohort Study. J Cardiothorac Vasc Anesth. 2015;29(6):1472-1479.
  • 9. Zhang WY, Wu WL, Gu JJ, et al. Risk factors for postoperative delirium in patients after coronary artery bypass grafting: A prospective cohort study. J Crit Care. 2015;30(3):606-612.
  • 10. Chang YL, Tsai YF, Lin PJ, Chen MC, Liu CY. Prevalence and risk factors for postoperative delirium in a cardiovascular intensive care unit. Am J Crit Care. 2008;17(6):567-575.
  • 11. Koster S, Hensens AG, Schuurmans MJ, van der Palen J. Consequences of delirium after cardiac operations. Ann Thorac Surg. 2012;93(3):705-711.
  • 12.Krzych LJ, Wybraniec MT, Krupka-Matuszczyk I, et al. Detailed insight into the impact of postoperative neuropsychiatric complications on mortality in a cohort of cardiac surgery subjects: a 23,000-patient-year analysis. J Cardiothorac Vasc Anesth. 2014;28(3):448-457.
  • 13. Mangusan RF, Hooper V, Denslow SA, Travis L. Outcomes associated with postoperative delirium after cardiac surgery. Am J Crit Care. 2015;24(2):156-163.
  • 14. Smulter N, Lingehall HC, Gustafson Y, Olofsson B, Engstrom KG. Delirium after cardiac surgery: incidence and risk factors. Interact Cardiovasc Thorac Surg. 2013;17(5):790-796.
  • 15. Tse L, Schwarz SK, Bowering JB, Moore RL, Barr AM. Incidence of and Risk Factors for Delirium After Cardiac Surgery at a Quaternary Care Center: A Retrospective Cohort Study. J Cardiothorac Vasc Anesth. 2015;29(6):1472-1479.
  • 16. Gottschalk A, Hubbs J, Vikani AR, Gottschalk LB, Sieber FE. The Impact of Incident Postoperative Delirium on Survival of Elderly Patients After Surgery for Hip Fracture Repair. Anesth Analg. 2015;121(5):1336-1343.
  • 17. Guo Y, Jia P, Zhang J, Wang X, Jiang H, Jiang W. Prevalence and risk factors of postoperative delirium in elderly hip fracture patients. J Int Med Res. 2016;44(2):317-327.
  • 18. Lee KH, Ha YC, Lee YK, Kang H, Koo KH. Frequency, risk factors, and prognosis of prolonged delirium in elderly patients after hip fracture surgery. Clin Orthop Relat Res. 2011;469(9):2612-2620.
  • 19. Mosk CA, Mus M, Vroemen JP, et al. Dementia and delirium, the outcomes in elderly hip fracture patients. Clin Interv Aging. 2017;12:421-430.
  • 20. Yang Y, Zhao X, Dong T, Yang Z, Zhang Q, Zhang Y. Risk factors for postoperative delirium following hip fracture repair in elderly patients: a systematic review and meta-analysis. Aging Clin Exp Res. 2017;29(2):115-126.
  • 21. Zywiel MG, Hurley RT, Perruccio AV, Hancock-Howard RL, Coyte PC, Rampersaud YR. Health economic implications of perioperative delirium in older patients after surgery for a fragility hip fracture. J Bone Joint Surg Am. 2015;97(10):829-836.
  • 22. Gleason LJ, Schmitt EM, Kosar CM, et al. Effect of Delirium and Other Major Complications on Outcomes After Elective Surgery in Older Adults. JAMA Surg. 2015;150(12):1134-1140.
  • 23. Abelha FJ, Luis C, Veiga D, et al. Outcome and quality of life in patients with postoperative delirium during an ICU stay following major surgery. Crit Care. 2013;17(5):R257.
  • 24. Inouye SK, Marcantonio ER, Kosar CM, et al. The short-term and long-term relationship between delirium and cognitive trajectory in older surgical patients. Alzheimers Dement. 2016;12(7):766-775.
  • 25. Raats JW, van Eijsden WA, Crolla RM, Steyerberg EW, van der Laan L. Risk Factors and Outcomes for Postoperative Delirium after Major Surgery in Elderly Patients. PLoS One. 2015;10(8):e0136071.
  • 26. Veiga D, Luis C, Parente D, et al. Postoperative delirium in intensive care patients: risk factors and outcome. Rev Bras Anestesiol. 2012;62(4):469-483.
  • 27. Abawi M, Nijhoff F, Agostoni P, et al. Incidence, Predictive Factors, and Effect of Delirium After Transcatheter Aortic Valve Replacement. JACC Cardiovasc Interv. 2016;9(2):160-168.
  • 28. Eide LS, Ranhoff AH, Fridlund B, et al. Comparison of frequency, risk factors, and time course of postoperative delirium in octogenarians after transcatheter aortic valve implantation versus surgical aortic valve replacement. Am J Cardiol. 2015;115(6):802-809.
  • 29. Huded CP, Huded JM, Sweis RN, et al. The impact of delirium on healthcare utilization and survival after transcatheter aortic valve replacement. Catheter Cardiovasc Interv. 2016.
  • 30. Maniar HS, Lindman BR, Escallier K, et al. Delirium after surgical and transcatheter aortic valve replacement is associated with increased mortality. J Thorac Cardiovasc Surg. 2016;151(3):815-823.e811-812.
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