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What is Hypoxia Symptoms, Causes, Diagnosis, and Treatment
Mechanism of injury, associated outcome and intervention
Learn more about system hypoxia causing cerebral desaturation:
Mechanism of Injury
Pulse oximetry may be unreliable under cardiopulmonary bypass and circulatory arrest.1 Therefore, system hypoxia may be difficult to diagnose.
Because cerebral oximetry does not depend on pulsatile flow, it may be used to confirm the presence of hypoxemia2
Adjusting FiO2 from 30% to 100% in shunted and non-shunted patients undergoing carotid endarterectomy significantly increased regional cerebral oxygen saturation3
Associated Outcome
A retrospective study of adverse perfusion-related incidents during cardiopulmonary bypass determined that 6% of incidents were the results of failure of oxygen delivery4
Intervention
% of all interventions5
Increase inspired oxygen concentration
6
Mechanism of injury, associated outcome and intervention
Learn more about system hypoxia causing cerebral desaturation:
Mechanism of Injury
Pulse oximetry may be unreliable under cardiopulmonary bypass and circulatory arrest.1 Therefore, system hypoxia may be difficult to diagnose.
Because cerebral oximetry does not depend on pulsatile flow, it may be used to confirm the presence of hypoxemia2
Adjusting FiO2 from 30% to 100% in shunted and non-shunted patients undergoing carotid endarterectomy significantly increased regional cerebral oxygen saturation3
Associated Outcome
A retrospective study of adverse perfusion-related incidents during cardiopulmonary bypass determined that 6% of incidents were the results of failure of oxygen delivery4
1. Sessler DI. Pulse oximetry may not reliably assess peripheral perfusion. Anesthesiology. 1998;88(4):1129; author reply 1130. View Abstract
2. Shah N, Trivedi NK, Clack SL, Shah M, Shah PP, Barker S. Impact of hypoxemia on the performance of cerebral oximeter in volunteer subjects. Journal of neurosurgical anesthesiology. 2000;12(3):201-209. View Abstract
3. Picton P, Chambers J, Shanks A, Dorje P. The influence of inspired oxygen fraction and end-tidal carbon dioxide on post-cross-clamp cerebral oxygenation during carotid endarterectomy under general anesthesia. Anesth Analg. 2010;110(2):581-587. View Abstract
4. Mejak BL, Stammers A, Rauch E, Vang S, Viessman T. A retrospective study on perfusion incidents and safety devices. Perfusion. 2000;15(1):51-61. View Abstract
5. Deschamps A, Lambert J, Couture P, et al. Reversal of decreases in cerebral saturation in high-risk cardiac surgery. Journal of cardiothoracic and vascular anesthesia. 2013;27(6):1260-1266. View Abstract