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Medtronic / Clinical Solutions / Cerebral Desaturation during Cardiac Surgery / Causes / Malperfusion

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MECHANISM OF INJURY, ASSOCIATED OUTCOME AND INTERVENTION

Learn more about malperfusion causing cerebral desaturation:

Mechanism of Injury

  • Malperfusion results from pressurization of a false lumen within the aorta or its branch vessels resulting in reduced flow and cerebral ischemia.1 In patients undergoing surgical repair of acute type A aortic dissection, the incidence of cerebral malperfusion is 16-33%.2

Associated Outcome

  • The presence of malperfusion is associated with increased postoperative coma, delirium, and hospital mortality.1,3
Intervention % of all interventions4
Reposition Cannula 6.4

MECHANISM OF INJURY, ASSOCIATED OUTCOME AND INTERVENTION

Learn more about malperfusion causing cerebral desaturation:

Mechanism of Injury

  • Malperfusion results from pressurization of a false lumen within the aorta or its branch vessels resulting in reduced flow and cerebral ischemia.1 In patients undergoing surgical repair of acute type A aortic dissection, the incidence of cerebral malperfusion is 16-33%.2

Associated Outcome

  • The presence of malperfusion is associated with increased postoperative coma, delirium, and hospital mortality.1,3
Intervention % of all interventions4
Reposition Cannula 6.4

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  • 1. Pacini D, Leone A, Belotti LM, et al. Acute type A aortic dissection: significance of multiorgan malperfusion. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 2013;43(4):820-826. View Abstract
  • 2. Bonser RS, Ranasinghe AM, Loubani M, et al. Evidence, lack of evidence, controversy, and debate in the provision and performance of the surgery of acute type A aortic dissection. Journal of the American College of Cardiology. 2011;58(24):2455-2474. View Abstract
  • 3. Geirsson A, Szeto WY, Pochettino A, et al. Significance of malperfusion syndromes prior to contemporary surgical repair for acute type A dissection: outcomes and need for additional revascularizations. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 2007;32(2):255-262. View Abstract
  • 4. Deschamps A, Lambert J, Couture P, et al. Reversal of decreases in cerebral saturation in high-risk cardiac surgery. Journal of cardiothoracic and vascular anesthesia. 2013;27(6):1260-1266. View Abstract
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