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Medtronic / Products / Motility Testing / Endoflip Impedance Planimetry System

Overview

Detect motility disorders

Endoflip™ 300 provides real-time measurements of the pressure and dimensions of the esophagus during endoscopic evaluation and surgical procedures.1 Endoflip™ 300 is a well-tolerated, convenient way to assess esophageal motility that can inform the need to refer patents to high-resolution manometry.2,3 During surgical procedures Endoflip™ 300 gives real-time feedback that can reduce negative outcomes of procedures like Nissen fundoplication, Heller myotomy, and per-oral endoscopic myotomies.4–6

Risk information*:
Arrhythmia, Anaphylaxis, Aspiration/inhalation, Bacterial infection, Bleeding/hemorrhage, Death (for Esoflip procedures only), Delay to treatment/therapy, Dental trauma, Dysphagia, Gastrointestinal regurgitation (for Esoflip procedures only), Heartburn/indigestion (for Esoflip procedures only), Hypersensitivity/allergic reaction, Laceration of the esophagus, Misdiagnosis/misclassification, Pain, Perforation of the esophagu,s Thermal burn, Vasovagal response

1/2

Up to 50% of endoscopies for predominant esophageal reflux symptoms are negative.7​

1/3

One in three patients referred with ongoing symptoms while using PPIs doesn’t have GERD.8​

No pills

PPI use has been associated with osteoporosis and other risks.9

You need an objective means to help you diagnose GERD and motility disorders​

There are many types of motility disorders, and pinpointing the underlying cause of the patients symptoms can be challenging.10​

Endoflip™ 300 can provide information to aid in therapeutic decision making.11

Learn more

How does Flip™ technology work?

Endoflip™ technology uses high-resolution impedance planimetry to measure luminal geometry and pressure during volume-controlled distension. It helps you assess the mechanical properties of the esophageal wall and opening dynamics of the gastroesophageal junction in various esophageal diseases.​

Literature review

Read a synopsis of clinical publications involving the Endoflip™ impedance planimetry system.

Read review

Our product portfolio 

Endoflip™ 300 impedance planimetry system

Endoflip™ 300 uses a balloon catheter to display diameter estimates of the measurement area in real-time. It can measure and display diameter estimates at up to 16 points within the balloon. 

Endoflip™ 300 helps identify motility disorders by providing real-time pressure and dimension measurements in the esophagus, pylorus, and anal sphincters. 

Endoflip™ 300 provides real-time assessment of the lower esophageal sphincter (LES) myotomy during Heller myotomy or per-oral endoscopic myotomy (POEM) procedures.12

Endoflip™ Catheter w/pressure measurement

The Endoflip™ EF-322N and EF-325N measurement catheters are designed for use with the Endoflip™ impedance planimetry system. They have integrated pressure sensors for balloon pressure measurement.

Esoflip™ dilation catheter

The Esoflip™ ES-310 and ES-320 balloon catheters are indicated for use to dilate esophageal strictures due to esophageal surgery, primary gastroesophageal reflux, or radiation therapy.

The Esoflip™ ES-330 balloon catheter is used in a clinical setting to dilate the gastroesophageal junction (EGJ) to treat achalasia.

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Order Information
EF-301 Endoflip™ 300 pump system Each 1
EF-302 Endoflip™ 300 display system Each 1
EF-303 Endoflip™ 300 cart Each 1
EF-322N Endoflip™ Catheter w/pressure measurement 16 cm Box 5 EA/ box
EF-325N Endoflip™ Catheter w/pressure measurement 8 cm Box 5 EA/ box
ES-320 Esoflip™ dilation catheter 20 mm Box 5 EA/ box
ES-330 Esoflip™ dilation catheter 30 mm Box 5 EA/ box


 Note: ENDOFLIP300-KIT-01 includes: EF-301, EF-302, EF-303 

Order Information

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  • * For a full indications of use, contraindications, precautions, warnings, and potential adverse events, please refer to the Instructions for Use
  • 1. Endoflip™ 300 Platform Operator's Manual, PT00136604 (2023)
  • 2. Carlson, Dustin A., et al. "Esophageal motility classification can be established at the time of endoscopy: a study evaluating real-time functional luminal imaging probe panometry." Gastrointestinal endoscopy 90.6 (2019): 915–923.
  • 3. Farina, Domenico A., and Dustin A. Carlson. "Functional Luminal Imaging Probe (FLIP) as an Adjunctive Modality in Evaluation of Esophageal Dysmotility." Foregut 1.3 (2021): 286–295.
  • 4. Ilczyszyn A, Botha A. Feasibility of esophagogastric junction distensibility measurement during Nissen fundoplication. Dis Esophagus. 2014 Sep-Oct;27(7):637–44.
  • 5. Carlson, Dustin A. "Evaluation of esophageal motility during endoscopy with the functional luminal imaging probe." Techniques in Gastrointestinal Endoscopy 20.3 (2018): 107–113.
  • 6. Hirano, Ikuo, John E. Pandolfino, and Guy E. Boeckxstaens. "Functional lumen imaging probe for the management of esophageal disorders: expert review from the clinical practice updates committee of the AGA institute." Clinical Gastroenterology and Hepatology 15.3 (2017): 325–334.
  • 7. Muthusamy VR, Lightdale JR, Acosta RD, et al. The role of endoscopy in the management of GERD. Gastrointestinal Endoscopy. 2015;81(6):1305-1310. doi: 10.1016/j.gie.2015.02.021. ​
  • 8. Herregods, T. V. K., et al. Patients with refractory reflux symptoms often do not have GERD. Neurogastroenterology & Motility. 2015;27(9):1267-1273.​
  • 9. Vakil, N. Prescribing proton pump inhibitors: is it time to pause and rethink? Drugs. 2012; 72, (4): 437–445 (72):438.​
  • 10.  Chaudhury A, Mashimo H. Oropharyngeal & esophageal motility disorders. Current diagnosis & treatment: gastroenterology, hepatology and endoscopy. 2016;3:164.​
  • 11. Ahuja NK, Agnihotri A, Lynch KL. Esophageal distensibility measurement: impact on clinical management and procedure length. Dis Esophagus. 2017 Aug 1;30(8):1–8.
  • 12. Su B, Dunst C, Gould J, et al. Experience-based expert consensus on the intra-operative usage of the Endoflip impedance planimetry system. Surgical Endoscopy: And Other Interventional Techniques. 2021;35(6):2731-2742. doi:10.1007/s00464-020-07704-3.
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