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Resolute Onyx DES

Resolute Onyx DES for coronary artery disease

Resolute Onyx™ is a drug-eluting stent (DES) that's different by design, optimised for complex PCI, and proven safe and effective in real-world, high bleeding risk patients on 1-month dual antiplatelet therapy (DAPT).1

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Resolute Onyx stent product image on white background

Overview

Resolute Onyx DES is different by design to address your DES needs and a wide range of patient anatomies. It features:

  • Best-in-class deliverability2
  • Enhanced visibility with thinner struts2
  • Smooth side branch access2
  • Fast healing3
  • The broadest diameter range

Product Features

Best-in-class deliverability

Single-wire design

Resolute Onyx DES is made from a single wire, which gives it a fluid range of motion and provides the flexibility needed for best-in-class deliverability.2

Sinusoid formed wire detail on the Resolute Onyx DES

Sinusoid-formed wire

Close-up depiction of Resolute Onyx helical wrap

Helical wrap

Resolute Onyx laser-fused product

Laser-fused

The Only DES Designed from a Single Wire‡

  • Single-wire design provides a fluid range of motion and the conformability needed for superior strut apposition.2
  • BioLinx biocompatible polymer provides superior thromboresistance.4
  • When combined, fast healing occurs as evidenced by nearly 90% strut coverage at 30 days,3 providing the foundation for the Onyx ONE Global Trial.
  • The Onyx ONE Global Trial analysed real-world, high bleeding risk patients on 1-month DAPT treated with a Resolute Onyx DES or a BioFreedom™* DCS.
  • Results showed Resolute Onyx DES was safe and effective,1 providing the option to shorten DAPT in patients who are at high bleeding risk.
  • Based on these results, Resolute Onyx DES was the first DES CE-indicated for HBR patients on 1-month DAPT.
See the Onyx ONE Data

Enhanced visibility with thinner struts

Platinum-iridium core within Resolute Onyx DES increases visibility for accurate stent placement without compromising strut thickness.2
Resolute Onyx cobalt alloy shell and platinum-iridum core
  1. Cobalt alloy shell
  2. Platinum iridium core
Close-up of the Resolute Onyx cobalt alloy shell and platinum-iridium core

Smooth side branch access

Resolute Onyx DES has round struts to create a smooth passage when accessing the side branch and lower the propensity to catch during bifurcation procedures.2

Rounded strut cross-section
  1. Resolute Onyx DES

Illustration of Resolute Onyx DES rounded struts

Broadest diameter range

  • Complex PCI requires a broad DES size matrix to match a wide range of patient anatomies.
  • Resolute Onyx is the only DES with diameters ranging from 2.0 mm to 5.0 mm to treat a broad range of coronary vessel sizes.
Columns

    Diameter (mm)

    		          

    Stent Length (mm)

    Maximum Expansion
    Capabilities (MSID†) (mm) 

    2.00

    8

    12

    15

    18

    22

    26

    30

    —

    —

    3.50‡

    2.25

    8

    12

    15

    18

    22

    26

    30

    34

    38

    3.50‡

    2.50

    8

    12

    15

    18

    22

    26

    30

    34

    38

    3.50‡

    2.75

    8

    12

    15

    18

    22

    26

    30

    34

    38

    4.00‡

    3.00

    8

    12

    15

    18

    22

    26

    30

    34

    38

    4.00‡

    3.50

    8

    12

    15

    18

    22

    26

    30

    34

    38

    5.00‡

    4.00

    8

    12

    15

    18

    22

    26

    30

    34

    38

    5.00‡

    4.50

    —

    12

    15

    18

    22

    26

    30

    —

    —

    6.00‡

    5.00

    —

    12

    15

    18

    22

    26

    30

    —

    —

    6.00‡

    Product Details
    82.00 12RONYX20008X 15RONYX20012X 18RONYX20015X 22RONYX20018X 26RONYX20022X 30RONYX20026X 34RONYX20030X 38Stent Length (mm)N/A N/A
    82.25 12RONYX22508X 15RONYX22512X 18RONYX22515X 22RONYX22518X 26RONYX22522X 30RONYX22526X 34RONYX22530X 38Stent Length (mm)RONYX22534X RONYX22538X
    82.50 12RONYX25008X 15RONYX25012X 18RONYX25015X 22RONYX25018X 26RONYX25022X 30RONYX25026X 34RONYX25030X 38Stent Length (mm)RONYX25034X RONYX25038X
    82.75 12RONYX27508X 15RONYX27512X 18RONYX27515X 22RONYX27518X 26RONYX27522X 30RONYX27526X 34RONYX27530X 38Stent Length (mm)RONYX27534X RONYX27538X
    83.00 12RONYX30008X 15RONYX30012X 18RONYX30015X 22RONYX30018X 26RONYX30022X 30RONYX30026X 34RONYX30030X 38Stent Length (mm)RONYX30034X RONYX30038X
    83.50 12RONYX35008X 15RONYX35012X 18RONYX35015X 22RONYX35015X 26RONYX35022X 30RONYX35026X 34RONYX35030X 38Stent Length (mm)RONYX35034X RONYX35038X
    84.00 12RONYX40008X 15RONYX40012X 18RONYX40015X 22RONYX40018X 26RONYX40022X 30RONYX40026X 34RONYX40030X 38Stent Length (mm)RONYX40034X RONYX40038X
    84.50 12N/A 15RONYX45012X 18RONYX45015X 22RONYX45018X 26RONYX45022X 30RONYX45026X 34RONYX45030X 38Stent Length (mm)N/A N/A
    85.00  12N/A 15RONYX50012X 18RONYX50015X 22RONYX50018X 26RONYX50022X 30RONYX50026X 34RONYX50030X 38Stent Length (mm)N/A N/A

    Maximum expansion capabilities

    For reference only in markets where the Resolute Onyx coronary stent and the 0.25 mm expansion have been approved.

    Additional Resources

    Onyx ONE Global Trial

    First randomised, 1-month DAPT trial comparing a DES to a DES in ~2000 high bleeding risk patients on 1-month DAPT.

    Review the Data

    Resolute Onyx DES is optimised for complex PCI

    Resolute Onyx DES design exclusives make it ideal for complex cases.

    See How

    Bifurcation education

    View five techniques that highlight Resolute Onyx DES through endoscopic imaging captured inside an isolated and reanimated beating porcine heart.

    Visit and Bookmark (opens new window)
    The Resolute Onyx DES zotarolimus drug effectively inhibits neointimal growth while the exclusive, highly biocompatible BioLinx™ polymer contributes to minimal inflammation, low thrombotic risk,5 as well as rapid, complete, and functional endothelial healing.§4
    pdf Onyx One Results Brochure (.pdf) (opens new window)

    This brochure presents clinical evidence about Onyx One.

    307KB

    This brochure presents clinical evidence about Onyx One. (opens new window)

    Request more information

    Contact us (opens new window)
    *

    As per April 2021.

    †

    Medtronic and Medtronic logo are trademarks of Medtronic.  Third-party trademarks ("™†") belong to their respective owners.  All other brands are trademarks of a Medtronic entity.

    ‡

    Including Resolute Integrity™ DES, part of the Medtronic DES portfolio.

    §

    In porcine models.

    References

    1

    Windecker S, Latib A, Kedhi E, et al. Polymer-based or Polymer-free Stents in Patients at High Bleeding Risk. N Engl J Med. March 26, 2020;382(13):1208-1218.

    2

    Based on bench test data on file at Medtronic. May not be indicative of clinical performance.

    3

    Roleder T, Kedhi E, Berta B, et al. Short-term stent coverage of second-generation zotarolimus-eluting durable polymer stents: Onyx one-month optical coherence tomography study. Adv Interv Cardiol. 2019;15(2):143-150.

    4

    Jinnouchi H, Sato Y, Cheng Q, et al. Int J Cardiol. March 2021;327:52-57.