Protect with confidence1 your patient's healthy parathyroid tissue — and their quality of life2
Hypoparathyroidism after neck surgery is common3
Up to
22%
of thyroid surgeries result in incendental parathyroid removal4
Up to
15%
of total thyroidectomies result in permanent hypoparathyroidism5
Up to
85%
of permanent hypoparathyroidism results from neck surgeries5
This puts patients as risk for hypoparathyroidism — a condition associated with a number of short- and long-term complications.2,6-10
3.1x greater risk of
renal insufficienty7
4x greater risk of
nephrolithiasis7
Neurocognitive
symptoms2,6,8
Cardiac
complications9,10
The burden of hypoparathyroidism is high.
Hypoparathyroidism after total thyroidectomy
- Increases the incidence of temporary hypocalcemia to 40%11
- Hypocalcemia is a common reason for hospital readission12
- Incidental parathyroid removal increases the incidence of permanent hypocalcemia to 5.8%11
Patients with hypoparathyroidism often require emergency care 41%.13
Impact on the quality of life2
In a study with a sample size of n= 397 patients.
Patients with permanent, post-surgical hypoparathyroidism may experience increased mortality after total thyroidectomy.3
Ready to change the numbers?
Up to 96% accuracy with Medtronic PTeye™ parathyroid detection system in confirming parathyroid tissue already visually located -providing greater surgeon confidence.14
Real-time confirmation: Up to 96% accuracy in confirming the parathyroid gland¹⁴
When identified with medium confidence, PTeye™ was highly beneficial for further improving the surgeon's confidence in:
Confirming parathyroid gland tissue in 88.9% (24/27) of the cases 1
Preventing surgeon error in 7.4% of times (2/27) where the surgeon misidentified non‐parathyroid tissue as parathyroid gland tissue1
Discover the PTeye™ system
The PTeye™ parathyroid detection system is an intra-operative probe-based technology to aid you in confirming suspected parathyroid tissue during thyroid and parathyroid surgery.14
1
Kiernan CM, Thomas G, Baregamian N, Solόrzano CC. Initial clinical experiences using theintraoperative probe-based parathyroid autofluorescence identification system—PTeye™during thyroid and parathyroid procedures. J Surg Oncol. 2021;124:271–281.
2
Siggelkow H, Clarke BL, Germak J, et al. Burden of illness in not adequately controlled chronic hypoparathyroidism: Findings from a 13-country patient and caregiver survey. ClinEndocrinol (Oxf). 2020 Feb;92(2):159–168. doi: 10.1111/cen.14128. Epub 2019 Dec 11. PMID:31721256; PMCID: PMC7027891.
3
Almquist M, Ivarsson K, Nordenström E, et al. Mortality in patients with permanenthy poparathyroidism after total thyroidectomy. Br J Surg. 2018 Sep;105(10):1313–1318. doi:10.1002/bjs.10843. Epub 2018 Apr 17. PMID: 29663312.
4
Applewhite M. et al Incidence, Risk Factors, and Clinical Outcomes of Incidental Parathyroidectomy During Thyroid Surgery, Ann Surg Oncol 2016 Dec; 23(13):4310–4315. doi: 10.1245/s10434-016-5439-1. Epub 2016 Aug 19. PMID: 27541813.
5
Sitges Serra et al Etiology and Diagnosis of Permanent Hypoparathyroidism after Total Thyroidectomy. J Clin Med 2021 Feb; Pg.4; 10(3): 543. doi:10.3390/jcm10030543
6
Büttner M, Singer S, Taylor K. Quality of life in patients with hypoparathyroidism receivingstandard treatment: an updated systematic review. Endocrine. 2024 Apr 5. doi:10.1007/s12020-024-03807-2. Epub ahead of print. PMID: 38578400.
7
Underbjerg L, Sikjaer T, Mosekilde L, Rejnmark L. Cardiovascular and renal complications to postsurgical hypoparathyroidism: a Danish nationwide controlled historic follow-up study. JBone Miner Res. 2013 Nov;28(11):2277–85. doi: 10.1002/jbmr.1979. PMID: 23661265.
8
Underbjerg L, Sikjaer T, Mosekilde L, Rejnmark L. Postsurgical hypoparathyroidism-risk offractures, psychiatric diseases, cancer, cataract, and infections. J Bone Miner Res. 2014 Nov;29(11):2504–10. doi: 10.1002/jbmr.2273. PMID: 24806578.
9
Underbjerg L, Sikjaer T, Rejnmark L. Long-Term Complications in Patients WithHypoparathyroidism Evaluated by Biochemical Findings: A Case-Control Study. J Bone MinerRes. 2018 May;33(5):822–831. doi: 10.1002/jbmr.3368. Epub 2018 Feb 14. PMID: 29281760.
10
Gosmanova EO, Chen K, Ketteler M, et al. Risk of Cardiovascular Conditions in Patients withChronic Hypoparathyroidism: A Retrospective Cohort Study. Adv Ther. 2021 Aug;38(8):4246–4257. doi: 10.1007/s12325-021-01787-7. Epub 2021 Jun 24. PMID: 34165700; PMCID: PMC8342323.
11
Bai B, Chen Z, ChenW(2018) Risk factors and outcomes of incidental parathyroidectomy in thyroidectomy: A systematic review and meta-analysis. PLoS One. 2018; 13(11): e0207088. doi: 10.1371/journal.pone.0207088. PMCID: PMC6226183 PMID: 304126393.
12
Taye A., Inabnet W., Pan S., et al. Post-thyroidectomy emergency room visits and readmissions: Assessment from the Collaborative Endocrine Surgery Quality Improvement Program (CESQIP). Am J Surg 2020 Oct;220(4):813–820. doi: 10.1016/j.amjsurg.2020.02.036. Epub 2020 Feb 19
13
Chen Ket al. A retrospective, cross-sectional physician-administered chart review of 614 patients with hypoparathyroidism. Patients were evaluated over a 1-year period. The study evaluated hypoparathyroidism-related healthcare resource utilizations, symptoms, comorbidities, and laboratory value.
14
PTeye IFU M012700C001