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Today, 250,000 people in the U.S. are diagnosed annually with symptomatic severe aortic stenosis (SSAS).1-9
After developing symptomatic severe aortic stenosis, the average patient survival is two years without treatment.11
Aortic stenosis is among the most common of all valvular heart diseases and continues to increase as our population ages.12 Symptomatic severe aortic stenosis (SSAS) can be fatal if left untreated.
DUE TO THE FOLLOWING FACTORS, SSAS ISN'T ALWAYS EASY TO DIAGNOSE OR TREAT:
Mortality difference for people with symptoms of aortic stenosis treated with aortic valve replacement versus those not undergoing this procedure is one of the most striking in medicine.12
Know more about Aortic Stenosis- Symptoms and Treatment Options HERE.
STS Adult Cardiac Database. 2010 Harvest, Isolated AVR.
Bach DS, Cimino N, Deeb GM. Unoperated patients with severe aortic stenosis. J Am Coll Cardiol. November 13, 2007;50(20):2018-2019.
Pellikka PA, Sarano ME, Nishimura RA, et al. Outcome of 622 adults with asymptomatic, hemodynamically significant aortic stenosis during prolonged follow-up. Circulation. June 21, 2005;111(24):3290-3295.
Charlson E, Legedza AT, Hamel MB. Decision-making and outcomes in severe symptomatic aortic stenosis. J Heart Valve Dis. May 2006;15(3):312-321.
Nkomo VT, Gardin JM, Skelton TN, Gottdiener JS, Scott CG, Enriquez-Sarano M. Burden of valvular heart diseases: a population-based study. Lancet. September 16, 2006;368(9540):1005-1011.
Lindroos M, Kupari M, Heikkilä J, Tilvis R. Prevalence of aortic valve abnormalities in the elderly: an echocardiographic study of a random population sample. J Am Coll Cardiol. April 1993;21(5):1220-1225.
Mack MJ, Brennan JM, Brindis R, et al. Outcomes following transcatheter aortic valve replacement in the United States. JAMA. November 20, 2013;310(19):2069-2077.
Medtronic data on file #1.
lung B, Baron G, Butchart EG, et al. A prospective survey of patients with valvular heart disease in Europe: The Euro Heart Survey on Valvular Heart Disease. Eur Heart J. July 2003;24(13):1231-1243.
Bavaria JE. TAVR Update: New Insights and Perspectives from the U.S. National STS/ACC TVT Registry. Available from STS National Database.
Ross J Jr, Braunwald E. Aortic stenosis. Circulation. July 1968; 38(1 Suppl):61-67.
Carabello BA, Paulus WJ. Aortic stenosis. Lancet. March 14, 2009;373(9667):956-966.
McCarthy CP, Phelan D, Griffin B. When does asymptomatic aortic stenosis warrant surgery? Assessment techniques. Cleve Clin J Med. April 2016;83(4):271-280.
Brennan JM. Under-treatment of Aortic Stenosis in the United States. Presented at TVT 2019; Chicago, IL.
Medtronic data on file #2; ZS Research; 2019.
Schwarz F, Baumann P, Manthey J, et al. The effect of aortic valve replacement on survival. Circulation. November 1982;66(5):1105-1110.
Active Living Awareness Initiative Survey. Survey included 3400 respondents. Available at: Heart-Valve-Surgery.com.
Disclaimer- The information mentioned herein are only intended for general awareness of the public and is not to be construed as a medical opinion and/or a diagnosis of any medical condition. You are required to use your own judgment and consult an appropriate registered medical practitioner for seeking any clarification around the content mentioned in this representation.