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Overview

Perfecting your art. Advancing patient care.
Make a difference in post-anesthesia outcomes.

You want the best outcomes for your patients. So, delivering just the right dose of anesthetic agent to personalize care is essential.

In a simple, configurable interface, the completely redesigned BIS™ Advance monitor helps you personalize anesthesia dosing.

Using less anesthesia can lead to faster extubation and faster discharge from the PACU for optimized patient throughput and a more efficient workflow.1

MORE INSIGHTS.
FOR A MORE PERSONALIZED ANESTHETIC APPROACH.

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Meet The BIS™ Advance monitor

Simple to read — large, high-resolution touchscreen monitor

See the information you want — configurable data and settings

Quickly review readings — color-coordinated data

Features

  1. EMG (electromyogram) shown in numerical and as a bar
  2. SQI (signal quality index)
  3. BIS™ value (with alarm range if programmed)
  4. SR (suppression ratio) percentage (with alarm limit if programmed)
  5. ST (suppression time) in minutes and seconds
  6. MF (median frequency)
  7. SEF (spectral edge frequency)
  8. Adjustable EEG amplitude scale and sweep speed
  9. Built-in troubleshooting guides
  10. Graphic display of BIS™ value and secondary variable
  11. High-resolution DSA (density spectral array)
  12. Two or four channel capabilities

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Designed for more efficient workflow

  • Save time with data output protocols that enable connectivity to electronic medical records (EMRs).
  • Set system-wide default preferences to save time — no need to re-set every time.
  • Maintain continuous monitoring when moving between care settings.

See the evidence for the BIS™ proven algorithm.

A circular illustration representing 38 percent

Use up to 38% less anesthetic agents to help control cost.1–5

A circular illustration representing a 27 to 53 percent range

Patients monitored with BIS™ technology wake up 27-53% faster in the OR.1,3,5,6

A circular illustration representing 87 percent

Patients monitored with BIS™ technology are 87% more fully awake and oriented upon arrival in the PACU and ready for discharger faster.1,5

BIS™ Advance for TIVA

BIS™ Advance for Enhanced Recovery After Surgery

BIS™ Advance for postoperative delirium (POD)

Clinical evidence

Improved post anesthesia recovery

"The pooled data showed that the use of BIS was significantly associated with a lower incidence of POCD and improved recovery parameters (extubation time, time to eye opening, and time to discharge from the PACU)."

– Wei Zhuen Chew et al, Bispectral Index (BIS) Monitoring and Postoperative Delirium in Elderly Patients Undergoing Surgery: A Systematic Review and Meta-Analysis With Trial Sequential Analysis

Chew WZ, Teoh WY, Sivanesan N, San Loh P, Shariffuddin II, Ti LK, Ng KT. Bispectral index (BIS) monitoring and postoperative delirium in elderly patients undergoing surgery: A systematic review and meta-analysis With trial sequential analysis. Journal of Cardiothoracic and Vascular Anesthesia. 2022 Dec 1;36(12):4449–59.

Improved post anesthesia neurocognitive outcomes

"We found that BIS monitoring of the depth of anesthesia prevented POD, whereas EEG monitoring was not effective. BIS quantifies the depth of anesthesia based on EEGs, which enables a more accurate control of anesthetic concentration and increases patient safely."

– Xia Li et al, Effects of perioperative interventions for preventing postoperative delirium

Li X, Wang Y, Liu J, Xiong Y, Chen S, Han J, Xie W, Wu Q. Effects of perioperative interventions for preventing postoperative delirium: A protocol for systematic review and meta-analysis of randomized controlled trials. Medicine. 2021 Jul 7;100(29)

Intraoperative awareness prevention

"…in intravenous anesthesia, BIS monitoring could reduce the incidence of intraoperative awareness by approximately 80%."

– Wen-Wei Gao, et al., in a clinical review on BIS monitoring on interoperative awareness

Gao, Ww., He, Yh., Liu, L. et al. BIS Monitoring on Intraoperative Awareness: A Meta-analysis. Curr Med Sci. 38, 349–353 (2018). https://doi.org/10.1007/s11596-018-1886-1

Educational Opportunities

Access training portal

Brain monitoring training pathways

Listen to MedEd podcast

Interview-style discussions on anesthesia and the brain

Check MedEd Bytes

A "byte"-sized educational video series

Watch webinars

A library of brain monitoring webinars

Learn about the BIS™ Advance monitor at your own pace with our in-depth training modules.

BIS™ Advance resources

BIS™ Advance brochure

BIS™ Advance TIVA brochure

BIS™ Advance Enhanced Recovery After Surgery brochure

Operators manual library

From this site you can view, print or order technical manuals free of charge for many Medtronic products.

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BIS™ Bilateral Sensor

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BIS™ Extended Use Sensor

BIS™ Extended Use Sensor

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BIS™ Pediatric Sensor

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  • The BIS™ monitoring system* should not be used as the sole basis for diagnosis or therapy and is intended only as an adjunct in patient assessment. Reliance on the BIS™ monitoring system alone for intraoperative anesthetic management is not recommended.

  • 1. Lewis SR, Pritchard MW, Fawcett LJ, Punjasawadwong Y. Bispectral index for improving intraoperative awareness and early postoperative recovery in adults. Cochrane Database System Review. 2019;9:CD003843. doi:10.1002/14651858.CD003843.pub4.

  • 2. Punjasawadwong Y, Phongchiewboon A, Bunchungmongkol N. Bispectral index for improving anaesthetic delivery and postoperative recovery. Cochrane Database Syst Rev. 2014;(6):CD003843. doi:10.1002/14651858.CD003843.pub3.

  • 3. Song D, Joshi GP, White PF. Titration of volatile anesthetics using bispectral index facilitates recovery after ambulatory anesthesia. Anesthesiology. 1997;87(4):842–848.

  • 4. Luginbühl M, Wüthrich S, Petersen-Felix S, Zbinden AM, Schnider TW. Different benefit of bispectal index (BIS) in desflurane and propofol anesthesia. Acta Anaesthesiol Scand. 2003;47(2):165–73.    ncbi.nlm.nih.gov/pubmed/12631045.

  • 5. Gan TJ, Glass PS, Windsor A, et al. Bispectral index monitoring allows faster emergence and improved recovery from propofol, alfentanil and nitrous oxide anesthesia. Anesthesiology. 1997;87(4):808–815. doi:10.1097/00000542-199710000-00014.

  • 6. Wong J, Song D, Blanshard H, Grady D, Chung F. Titration of isoflurane using BIS index improves early recovery of elderly patients undergoing orthopedic surgeries. Can J Anaesth. 2002;49(1):13–18. doi:10.1007/BF03020413.

  • * Licensed as EEG COMPLETE MONITORING SYSTEM

Corporate Resources
Minimally Invasive Therapies
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