SYMPLICITY SPYRAL™ RENAL DENERVATION (RDN) SYSTEM

Education and resources

Renal denervation for hypertension

Find courses, webinars, and other educational activities for hypertension and the Symplicity™ blood pressure procedure (also called renal denervation).

  

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Long-term safety and efficacy of RDN

Professor Felix Mahfoud presents the SPYRAL HTN-ON MED pilot study data at ACC 2022 detailing the long-term safety and efficacy of renal denervation with the Symplicity blood pressure procedure.

A video featuring Profs. Felix Mahfoud, Roland Schmieder, and Flavio Ribichini discussing key findings on renal denervation (RDN).

MACE risk reductions

Professors Felix Mahfoud, M.D., Roland Schmieder, M.D., and Flavio Ribichini, M.D.,discuss key fndings on RDN.

Real-world outcomes

Professor Felix Mahfoud discusses real-
world outcomes of the Symplicity procedure from the GLOBAL SYMPLICITY REGISTRY.

The science of the procedure

Professor Andrew Sharp explores the science of the Symplicity blood pressure procedure from a proceduralist’s perspective.

Build your RDN knowledge

Browse online courses and many other educational resources about the Symplicity blood pressure procedure, clinical evidence, and practical clinical application.

A doctor walking in a hospital reviews information on a tablet screen.

Medscape education

Clinical advances in interventional innovations in blood pressure control. 

Medscape’s education platform helps physicians learn about recent data with innovative interventional technology that can help patients achieve blood pressure control as an alternative to, or in addition to, typical management plans that include anti-hypertensive medications and lifestyle modifcations.

Radcliffe medical education

Exploring RDN from fundamentals to patient selection to the future

Radcliffe offers CME courses and webinars exploring renal denervation, clinical data, and many other topics, featuring Prof. Stefano Taddei, Prof. Atul Pathak, Prof. Andrew Sharp, Prof. Roland Schmeider, and other distinguished faculty.

WONDR Medical

RDN:NOW

WONDR Medical regularly introduces training resources and a wide array of video content in multiple languages at RDN:NOW.

The homage page for RDN NOW, a collection of education resources from Wondr Medical.

American Heart Association

The education home page of the American Heart Association as shown on a laptop screen.

Unmet needs in hypertension treatment

The American Heart Association (AHA) offers a hypertension professional education series with new learning modules added regularly. Content includes webinars, spotlight series and podcasts.

American College of Cardiology

Overcoming challenges in hypertension management

This American College of Cardiology (ACC) education initiative platform helps learners evaluate and select evidence-based interventions and contemporary approaches for the treatment and control of hypertension.

Content includes webinars, podcasts, certifed cases, quick tip videos, gamifcation, patient case quizzes, and interactive cases/lessons.

 
The home page of the American College of Cardiology as shown in a laptop screen.
A clipboard icon represents the availability of resources for patient selection.

Select the right patients

See which types of patients could beneft from the Symplicity blood pressure procedure.

An open book icon represents the breadth of clinical evidence for the Symplicity procedure.

Extensive clinical evidence

The Symplicity blood pressure procedure is supported by multiple clinical trials and a real-world patient registry.1-4

Illustration of kidneys.

Transforming hypertension treatment

The Symplicity blood pressure procedure is changing how patients with hypertension can reduce their blood pressure.

1

Mahfoud F, Kandzari DE, Kario K, et al. Long-term efficacy and safety of renal denervation in the presence of antihypertensive drugs (SPYRAL HTN-ON MED): a randomised, sham-controlled trial. The Lancet. 2022;399:1401-1410.

2

Mahfoud F, Mancia G, Schmieder R, et al. Three-year safety and efficacy in the Global Symplicity Registry: Impact of antihypertensive medication burden on blood pressure reduction. Presented at PCR e-course 2020.

3

Böhm M, Kario K, Kandzari DE, et al. Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomised, sham-controlled trial. The Lancet. 2020;395:1444-1451.

4

Kandzari DE, Böhm M, Mahfoud F, et al. Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial. The Lancet. 2018;391(10137):2346.

  • Symplicity Spyral RDN System, Licensed as , SYMPLICITY SPYRAL MULTI ELECTRODE RENAL DENERVATION SYSTEM