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About the Medtronic Symplicity™ Procedure

  

BLOOD PRESSURE PROCEDURE

About the procedure

The renal denervation blood pressure procedure is an evidence-based option to help reduce high blood pressure.1-3

  

  

Illustration showing a cellphone held in a hand with a blood pressure reading on the screen

  

What makes the procedure different from traditional management options?

  • Single, minimally invasive procedure that can help reduce blood pressure – supported by safety and effectiveness evidence1-3
  • Works to reduce blood pressure 24 hours a day – unlike daily medications, which rely on taking pills every day to be effective1,2
  • Provides sustained blood pressure reductions – supported by long-term follow-up evidence to 10 years4

Adverse events include, but are not limited to, bruising and pain. Results may vary.

↓ 16.7

mmHg

In a three-year study of people who received the procedure, it helped reduce BP by 16.7 mmHg.1

Explore the science.

Learn more about how the renal denervation blood pressure procedure can help move blood pressure numbers in the right direction.1–3

See how it works

Beyond basic management for high blood pressure

See what happens during the renal denervation blood pressure procedure.

Get the details

About this procedure

Important information about the benefits and risks of the renal denervation blood pressure procedure

See benefits and risks

What to expect from the procedure

Learn more about what is involved in the renal denervation blood pressure procedure, and what to expect on the day of the procedure.

What to expect

Find more answers.

Dive into our FAQ about the renal denervation blood pressure procedure.

Read FAQ

Always follow the instructions specified by your doctor or the nursing staff. Always follow the discharge instructions provided by your physician after your procedure.

References

1

Mahfoud F, Kandzari DE, Kario K, et al. Long-term efficacy and safety of renal denervation in the presence of antihypertensive drugs (SPYRAL HTN-ON MED): a randomised, sham-controlled trial. The Lancet. 2022; 399(10234):1401–1410.

2

Kandzari DE, Böhm M, Mahfoud F, et al. Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial. Lancet. June 9, 2018;391(10137):2346–2355.

3

Böhm M, Kario K, Kandzari DE, et al. Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomised, sham-controlled trial. Lancet. May 2, 2020;395(10234):1444–1451.

4

Al Ghorani H, Kulenthrian S, Johannes M, et al. 10-Year Outcomes of Catheter-Based Renal Denervation in Patients With Resistant Hypertension. Journal of the American College of Cardiology. 2023;81(5):517-519